Successful academic practices foster student learning in a precise, efficient, and didactic manner. In this sense, the purpose of this research was to identify those academic practices that are considered successful by teachers and students of the universities of the department of Norte de Santander in Colombia that offer virtual programs in administrative sciences, as well as to know the collective imaginaries that are create around them. The research responded to a qualitative approach of the grounded theory type, using documentary review, semi-structured interview and focus group as information collection techniques. The analysis of results was carried out using the Atlas ti software, where the following categories emerge: knowledge management, entrepreneurship, university-business relationship, innovation in academic practices and organizational learning in educational settings. The results showed a varied number of practices classified as successful that, although they constitute an approach to the reality of work, the implementation of new technologies or intervention to solve business situations, require planning and execution from an inclusive curriculum built with the support of the company, the community and government entities, as well as anticipated regional research and development processes.